Telomerase as a Cancer Target with RNA Interference Someone was bound to get the idea to use RNA interference therapeutically sooner or later, and it just so happens that scientists at the University of Rochester have targeted telomerase as an RNAi candidate. The RNAi technique used by these researchers reduced, but did not completely inhibit, the activity of telomerase in in vitro cancer cells. If RNAi is analogously effective at disabling the activity of telomerase in vivo then this could significantly stop the growth of cancerous cells. Lead researcher commented "If we can develop a therapy that prevents cancer cells from making telomerase, we may have a therapy that is effective against most cancers." Funny he should say that, because that's exactly what Geron is doing, but not with RNAi. One of their mission-statement webpages reads that they are developing "anti-cancer therapies based on telomerase inhibitors, oncolytic viruses and telomerase vaccines." Telomerase is becoming a big target in the R&D world, and hopefully the research will pay off soon with effective cancer therapies.